Quatrefolic® vs. Folic Acid: Why Bioavailable Folate is Crucial for Pregnancy Health

Folate is essential for foetal development and overall pregnancy health, but not all forms of folate provide the same benefits. The two most common forms found in supplements and fortified foods are folic acid and reduced folate like Quatrefolic®. Understanding the differences between these forms is crucial when choosing a prenatal supplement to support your body and your baby's health during pregnancy.

Looking for a high-quality prenatal multivitamin? Check out our Preconception Multi for Women by NaturoBest, formulated with Quatrefolic® for optimal nutrient absorption.

What is the difference between folic acid and reduced folate (Quatrefolic®)?

Folic acid is a synthetic form of folate commonly found in fortified foods and supplements. However, before the body can use it, folic acid must be converted into its active form, 5-MTHF. Unfortunately, many people have genetic variations (such as MTHFR gene mutations) that hinder this conversion process, potentially leading to folate deficiencies and related health issues during pregnancy.

On the other hand, Quatrefolic® is a patented form of 5-MTHF that is already in its active form, meaning it doesn’t require conversion. This makes it immediately available for the body to use, ensuring better nutrient absorption and reducing the risk of folate deficiency during pregnancy.

Benefits of Reduced Folate During pregnancy?

Choosing a supplement with Reduced Folate like the NaturoBest Prenatal Trimester 2 & 3 Plus Breastfeeding, provides essential support during pregnancy. Quatrefolic® has been shown to offer several key benefits:

  • Reduces the risk of neural tube defects in the early stages of pregnancy.
  • Lowers the risk of preterm birth and low birth weight.
  • Helps support maternal mood, potentially reducing the risk of postpartum depression.

These benefits make Reduced Folate a superior choice compared to synthetic folic acid, especially for those who struggle with folate absorption.

Why Choose Quatrefolic® Over Folic Acid for Pregnancy?

Many prenatal supplements contain folic acid, but this form may not be the best option for everyone. Quatrefolic® has several advantages over folic acid:

  • No conversion needed: Quatrefolic® is already in its active form.
  • Greater bioavailability: It is more easily absorbed and utilized by the body, ensuring optimal support for both mother and baby.
  • Better tolerability: Many people find Quatrefolic® easier to tolerate than synthetic folic acid.

By choosing a supplement like the Prenatal Trimester 1 by NaturoBest, you can ensure that you’re getting the best form of folate to support your body and your baby's health during pregnancy.

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    References

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    5. Scaglione, F., & Panzavolta, G. (2014). Folate, folic acid and 5-methyltetrahydrofolate are not the same thing. Xenobiotica, 44(5), 480-488. https://doi.org/10.3109/00498254.2013.845705

    Quatrefolic® can be found in these premium supplements by NaturoBest